Dr. Ballester Clinic has a new service of Regenerative Therapy with Platelet Rich Plasma (PRP).
What are the growth factors?
They are proteins that develop essential functions in the processes of repair and regeneration of tissues. They are found in many cells and part of the body (macrophages, endothelial cells, monocytes, fibroblasts, bone matrix and platelets).
What is regeneration?
Regeneration is defined as the capacity of an organism to restore or reconstitute a lost or damaged structure on the other hand identical, which retains the structure and functionality to the original. Regenerative capacity behaves differently in invertebrate animals and in vertebrates. This capacity in vertebrates is very diminished or almost absent in most of its tissues.
When we suffer a wound, the human body immediately sets in motion the mechanisms to protect itself from possible infection and repair damaged tissues.
Repair process:
1. Haemostasis: blood vessels retract to reduce bleeding and platelets form a clot to stop bleeding
2. Cleaning phase: once the blood has coagulated, the vessels are dilated and leukocyte exudation takes place (they clean the area of dead tissues, foreign bodies and bacteria)
3. Granulation or reconstruction phase: the fibroblasts enter the scene to produce collagen that creates a matrix of tissue that facilitates cell migration and therefore the repair of said tissue
What do growth factors do?
These proteins intervene in the relationship between cells and transmit information by interacting with cellular receptors that are in the cell membrane. They are responsible for triggering biological effects such as cell migration, proliferation and cell differentiation. Fundamental processes for tissue repair and recovery.
Platelets:
Platelet alpha granules contain not only the growth factors that play the basic role in hemostasis or the healing of tissues such as PDGF, TGF, PDAF, PDEGF, EGF, TNF, LDGF, FGF and CTGF, but the proteins that act on cell adhesion, such as fibrin. , Fibronectin, Vitronectin. The generation of new blood vessels and fibrous tissue, as well as the growth-stimulated collagenesis facilitates the rapid regeneration of epithelial cells and improves the ability to heal wounds
In summary, platelets release large doses of bioactive proteins, known as growth factors responsible for attracting macrophages, mesenchymal stem cells and osteoblasts that promote the elimination of necrotic tissue and improve tissue regeneration and repair.
What is PRP?
It is the product obtained from autologous blood of the patient after having gone through a system of centrifugation and separation of the different components of the blood (Red blood cells, white blood cells, platelets and plasma).
What is achieved?
Depending on the different systems, a platelet count of at least 5 times greater than the baseline 1.000.000plaq / Ul / 5ml (Basal 150.000ul) will be obtained.
Parts that we get
1 red blood cells (Red blood cells)
2 White Globes
3 Plasma poor in PRP (but rich in fibrin)
4 platelet rich plasma (PrP)
Parties that we infiltrate
What can we use PRP for?
-In traumatology:
Joint injuries
Tendinous, meniscal and ligament injuries
Muscle, fascia and soft tissue injuries
Intervertebral disc disease
Arthroplasties
Surgical wounds
Avascular necrosis
Biointegration of grafts, prostheses and biomaterials
-In dentistry:
Wound healing
Mucogingival surgery
Promotes osseointegration of dental implants
For more information, call 96 578 09 55 or visit their facilities at Calle Marques de Campo, 27 3ºA.
